Knowledge

What is Cortisol?

Cortisol is a steroid hormone produced by the adrenal glands that is released in response to stress¹.

It plays a crucial role in regulating various bodily functions, including metabolism, immune response, and the sleep-wake cycle¹. In stressful situations, cortisol provides the body with glucose by tapping into protein stores via gluconeogenesis in the liver. This energy can help an individual activate the fight or flight response². However, chronic stress can cause prolonged cortisol production, which can disrupt the gut microbiome and contribute to mental disorders such as anxiety and depression.

References

  1. Galland, L. (2014) The gut microbiome and the brain, Journal of medicinal food. U.S. National Library of Medicine. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259177/ (Accessed: November 25, 2022).

  2. Madison, A. and Kiecolt-Glaser, J.K. (2019)Stress, depression, diet, and the gut microbiota: Human-bacteria interactions at the core of psychoneuroimmunology and Nutrition, Current opinion in behavioral sciences. U.S. National Library of Medicine. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213601/ (Accessed: November 26, 2022).

On this page